Test Code THYRZ (THYRO) Thyrotropin Receptor Antibody, Serum
Reporting Name
Thyrotropin Receptor Ab, SUseful For
Recommended first-line test for detection of thyrotropin receptor antibodies
The following situations:
-Differential diagnosis of etiology of thyrotoxicosis in patients with ambiguous clinical findings and/or contraindicated (eg, pregnant or breast-feeding) or nondiagnostic thyroid radioisotope scans
-Diagnosing clinically suspected Graves disease (GD) (eg, extrathyroidal manifestation of GD include endocrine exophthalmos, pretibial myxedema, thyroid acropachy) in patients with normal thyroid function tests
-Determining the risk of neonatal thyrotoxicosis in a fetus of a pregnant female with active or past active GD
-Differential diagnosis of gestational thyrotoxicosis versus first trimester manifestation or recurrence of GD
-Assessing the risk of GD relapse after antithyroid drug treatment
Performing Laboratory
Mayo Clinic Laboratories in RochesterSpecimen Type
SerumSpecimen Required
Patient Preparation:
1. For 12 hours before specimen collection do not take multivitamins or dietary supplements containing biotin (vitamin B7), which is commonly found in hair, skin, and nail supplements and multivitamins.
2. Patient should not be receiving heparin treatment.
Collection Container/Tube:
Preferred:Â Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
0.75 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Serum | Refrigerated (preferred) | 7 days | |
Frozen | 90 days |
Reference Values
≤1.75 IU/L
Day(s) Performed
Monday through Saturday
Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
83520
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
THYRO | Thyrotropin Receptor Ab, S | 5385-0 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
THYRO | Thyrotropin Receptor Ab, S | 5385-0 |
Report Available
1 to 3 daysReject Due To
Gross hemolysis | Reject |
Gross lipemia | OK |
Gross icterus | Reject |
Method Name
Electrochemiluminescence Immunoassay
Forms
If not ordering electronically, complete, print, and send a General Request (T239) with the specimen.